Generic Viagra (Sildenafil) Pills

I had the dubious distinction last year of being mocked (in absentia) on national TV by Jay Leno, who for some unimaginable reason found it amusing that a guy named Harder had written a news story about flaccidity.

Headline jokes aside, erectile dysfunction is a serious matter, and not just because it can threaten the health of a marriage. More than just a sexual problem, ED is often a sign that a man’s life is at risk. That was the point of my report last year, and the evidence behind it has only grown stronger. On this day, the tenth anniversary of Viagra’s regulatory approval by the Food and Drug Administration, I decided to look anew at that evidence. (If you’re more interested in the drug itself than in the condition it treats, check out these five things about the blue pill that you might not know.)

• Thirty million men in the United States have erectile dysfunction, according to an estimate reported this month, and the number is expected to double by 2025.
• Erectile dysfunction often appears in combination with other chronic health conditions. About half of men with diabetes and about half of those with heart disease also have ED, UCLA urologist Christopher Saigal and his colleagues reported in 2006. More than a third of men with high blood pressure have ED, they found.
• Researchers have also found that men with ED often have diabetes, heart disease, and other medical problems. A large study published last year found that 20 percent of men with ED had diabetes compared with 7.5 percent of the men who didn’t have ED. In many cases, those ailments haven’t yet been diagnosed when the man seeks out Viagra or another treatment for his sexual problem.
• Some doctors say they’re now testing men who complain of ED to see if they need treatment for undiagnosed diabetes or heart disease. An erectile problem may be a “sentinel sign” of undiagnosed cardiovascular disease, according to researchers such as Allen D. Seftel, a urologist at Case Medical Center in Cleveland.
• Physical activity may stave off—or even reverse—erectile problems. An Austrian study published this month found that men who burn at least 3,000 kilocalories (aka calories) per week through physical activity were 82.9 percent less likely to have erectile dysfunction than men who perform less than 3,000 calories’ worth of activity per week. In an earlier trial lasting two years, men were more likely to recover erectile function if they adopted lifestyle changes that increased their physical activity and led them to lose weight.

I’m interested in hearing comments—anonymous is fine—from men who have erectile dysfunction. When you sought medical attention for the condition, did your doctor investigate whether you had heart disease, diabetes, or another similar condition?

Viagra and related erectile dysfunction drugs appear to counteract sexual dysfunction in some women taking antidepressants. But those pills aren’t going to help all depressed women overcome a common side effect of their psychiatric medication. Depressed women whose testosterone levels are low are particularly unlikely to find sexual function restored by Viagra, says Anita Clayton, professor of psychiatry at the University of Virginia and an expert in treatment-related sexual problems. Furthermore, Viagra can cause its own side effects, from headache to flushing, and can’t be taken with nitrates, drugs typically prescribed for chest pain.

So, here are four alternatives to Viagra for women whose sexual problems are linked to taking an antidepressant:

1. Give it time. Since depression itself can dampen sexual function, Clayton advises waiting to try Viagra and other possible antidotes until the depression has been sufficiently tamed with medication. Also, antidepressant-related sexual side effects will sometimes dissipate on their own, says Robert Taylor Segraves, a professor of psychiatry at Case Western Reserve University, although it may take at least three to five months to do so.

2. Switch antidepressants. Sometimes switching to antidepressants that have lower risks of sexual side effects is an option, says Clayton, like bupropion (marketed as Wellbutrin), which doesn’t interact with serotonin, the neurotransmitter that many antidepressants increase and is thought to be responsible for some of the sexual trouble.

3. Dose it down. In some cases, lowering the dose of an antidepressant may rid patients of their medication-induced sexual troubles, but doing so runs the risk of losing the antidepressant’s effect, says Segraves. Neither Segraves nor Clayton recommends taking an “antidepressant vacation,” although some doctors may suggest it. The danger: Interrupted treatment can lead to medication abandonment, withdrawal symptoms, or return of depression.

4. Other antidotes. The antianxiety drug buspirone (marketed as BuSpar) is thought to be another off-label antidote to sexual dysfunction induced by antidepressants, says Segraves.

• Viagra name: Sildenafil Citrate
•     Viagra approved as an impotence pill by US Food and Drug Administration (FDA) 27 March 1998, less than 6 months after Viagra’s submission
•     Viagra is made by Pfizer Pharmaceuticals, New York N.Y.
•     300,000 Viagra scripts written in three weeks in US
•     Viagra costs $10 a pill in US
•     Recommended dose is 50mg an hour before effect is desired - some need 100mg Viagra, others need only 25mg. Viagra should only be used maximum of once a day.
•     Viagra side effects are headache, flushing and indigestion. 3% report changes in vision - mainly colour perception.
•     Drop-out rates in treatment were low - 2.5% on Viagra compared to 2.3% on placebo
•     Viagra confers no resistance to AIDS or other sexually transmitted diseases and may increase risky behaviour.