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For Women, 4 Alternatives to Viagra

August 13th, 2008 by admin

Viagra and related erectile dysfunction drugs appear to counteract sexual dysfunction in some women taking antidepressants. But those pills aren’t going to help all depressed women overcome a common side effect of their psychiatric medication. Depressed women whose testosterone levels are low are particularly unlikely to find sexual function restored by Viagra, says Anita Clayton, professor of psychiatry at the University of Virginia and an expert in treatment-related sexual problems. Furthermore, Viagra can cause its own side effects, from headache to flushing, and can’t be taken with nitrates, drugs typically prescribed for chest pain.

So, here are four alternatives to Viagra for women whose sexual problems are linked to taking an antidepressant:

1. Give it time. Since depression itself can dampen sexual function, Clayton advises waiting to try Viagra and other possible antidotes until the depression has been sufficiently tamed with medication. Also, antidepressant-related sexual side effects will sometimes dissipate on their own, says Robert Taylor Segraves, a professor of psychiatry at Case Western Reserve University, although it may take at least three to five months to do so.

2. Switch antidepressants. Sometimes switching to antidepressants that have lower risks of sexual side effects is an option, says Clayton, like bupropion (marketed as Wellbutrin), which doesn’t interact with serotonin, the neurotransmitter that many antidepressants increase and is thought to be responsible for some of the sexual trouble.

3. Dose it down. In some cases, lowering the dose of an antidepressant may rid patients of their medication-induced sexual troubles, but doing so runs the risk of losing the antidepressant’s effect, says Segraves. Neither Segraves nor Clayton recommends taking an “antidepressant vacation,” although some doctors may suggest it. The danger: Interrupted treatment can lead to medication abandonment, withdrawal symptoms, or return of depression.

4. Other antidotes. The antianxiety drug buspirone (marketed as BuSpar) is thought to be another off-label antidote to sexual dysfunction induced by antidepressants, says Segraves.

Viagra facts

August 5th, 2008 by admin
  • Viagra name: Sildenafil Citrate
  •     Viagra approved as an impotence pill by US Food and Drug Administration (FDA) 27 March 1998, less than 6 months after Viagra’s submission
  •     Viagra is made by Pfizer Pharmaceuticals, New York N.Y.
  •     300,000 Viagra scripts written in three weeks in US
  •     Viagra costs $10 a pill in US
  •     Recommended dose is 50mg an hour before effect is desired - some need 100mg Viagra, others need only 25mg. Viagra should only be used maximum of once a day.
  •     Viagra side effects are headache, flushing and indigestion. 3% report changes in vision - mainly colour perception.
  •     Drop-out rates in treatment were low - 2.5% on Viagra compared to 2.3% on placebo
  •     Viagra confers no resistance to AIDS or other sexually transmitted diseases and may increase risky behaviour.

Scientists: Watermelon yields Viagra-like effects

July 31st, 2008 by admin

A slice of cool, fresh watermelon is a juicy way to top off a Fourth of July cookout and one that researchers say has effects similar to Viagra — but don’t necessarily expect it to keep the fireworks going all night long.

Watermelons contain an ingredient called citrulline that can trigger production of a compound that helps relax the body’s blood vessels, similar to what happens when a man takes Viagra, said scientists in Texas, one of the nation’s top producers of the seedless variety.

Found in the flesh and rind of watermelons, citrulline reacts with the body’s enzymes when consumed in large quantities and is changed into arginine, an amino acid that benefits the heart and the circulatory and immune systems.

“Arginine boosts nitric oxide, which relaxes blood vessels, the same basic effect that Viagra has, to treat erectile dysfunction and maybe even prevent it,” said Bhimu Patil, a researcher and director of Texas A&M’s Fruit and Vegetable Improvement Center. “Watermelon may not be as organ-specific as Viagra, but it’s a great way to relax blood vessels without any drug side effects.”

Todd Wehner, who studies watermelon breeding at North Carolina State University, said anyone taking Viagra shouldn’t expect the same result from watermelon.

“It sounds like it would be an effect that would be interesting but not a substitute for any medical treatment,” Wehner said.

The nitric oxide can also help with angina, high blood pressure and other cardiovascular problems, according to the study, which was paid for by the U.S. Department of Agriculture.

More citrulline — about 60 percent — is found in watermelon rind than in the flesh, Patil said, but that can vary. But scientists may be able to find ways to boost the concentrations in the flesh, he said.

Citrulline is found in all colors of watermelon and is highest in the yellow-fleshed types, said Penelope Perkins-Veazie, a USDA researcher in Lane, Okla.

She said Patil’s research is valid, but with a caveat: One would need to eat about six cups of watermelon to get enough citrulline to boost the body’s arginine level.

“The problem you have when you eat a lot of watermelon is you tend to run to the bathroom more,” Perkins-Veazie said.

Watermelon is a diuretic and was a homeopathic treatment for kidney patients before dialysis became widespread.

Another issue is the amount of sugar that much watermelon would spill into the bloodstream — a jolt that could cause cramping, Perkins-Veazie said.

Patil said he would like to do future studies on how to reduce the sugar content in watermelon.

The relationship between citrulline and arginine might also prove helpful to those who are obese or suffer from type-2 diabetes. The beneficial effects — among them the ability to relax blood vessels, much like Viagra does — are beginning to be revealed in research.

Citrulline is present in other curcubits, like cucumbers and cantaloupe, at very low levels, and in the milk protein casein. The highest concentrations of citrulline are found in walnut seedlings, Perkins-Veazie said.

“But they’re bitter and most people don’t want to eat them,” she said.

Viagra may offer help for enlarged hearts

July 17th, 2008 by admin

Viagra may aid in the treatment of enlarged hearts that can result from high blood pressure, tests on animals indicate.

Plans are under way for a trial to determine if similar results occur in humans given the drug widely used to treat erectile dysfunction.

The drug, known generically as sildenafil citrate, blocked and even reversed some of the heart enlargement in mice with blood pressure stress, said researchers led by Dr. David A. Kass of the Johns Hopkins University School of Medicine.

“A larger-than-normal heart is a serious medical condition, known as hypertrophy, and is a common feature of heart failure that can be fatal,” Kass said.

He said the findings “suggest possible therapies in the future, including sildenafil, which has the added benefit of already being studied as safe and effective for another medical condition” — male sexual dysfunction.

The report, in Sunday’s online edition of Nature Medicine, came as no surprise to Dr. William B. White, head of the hypertension section of the University of Connecticut Health Center.

White, who was not part of Kass’ research team, noted that sildenafil originally was discovered by researchers studying blood pressure and heart disease.

History of Viagra

July 9th, 2008 by admin

Viagra was launched in mid April 1998 in the US, and was an instant hit to treat impotence and different degrees of erectile dysfunction. Within 14 days despite the high Viagra price, doctors were writing more than 110,000 Viagra scripts a week. In 14 weeks 2 million Viagra scripts had been written in the US alone and Viagra had become established as a new recreational drug in club culture world-wide, though non-medical supplies were rare in many countries with smuggled Viagra tablets fetching over $100 each.

Soon after, the reports of Viagra side effects began to climb. Substitute viagra, free viagra, herbal viagra, cheap viagra, viagra sale online, natural viagra, viagra alternative - Viagra sales leapt and so did sales of every kind of aphrodisiac on the impotence market, all promising more for less.

As a result of all this, Pfizer’s shares soared from $45 to $115. Wild claims were being made that Viagra had the power not only to cure impotence but also to give healthy, non-impotent older men the sexual performance of a twenty year old. Viagra created an overnight stampede to millions of physicians by a generation of perfectly normal and healthy men, looking for the greatest Viagra enhanced sex they’d had in years. Sex up to six times a night has been reported after normal men take Viagra.

Viagra story: Worth Three Times the Cost

June 28th, 2008 by admin

Amazing result, you don’t know how happy I am. Viagra changed my life. No anxiety about erection. This also solved premature ejaculation. After trying Viagra, even if they sold it at three times the price, I would still buy it. Those who didn’t try Viagra and passed away from this world are very unlucky! I am also a little unlucky, I wish I had try Viagra 3  years earlier. -  Vladimir, Russia, Age 54

Getting More Bang for Your Buck

June 16th, 2008 by admin

When I use Viagra the effects often last for up to several hours, sometimes after I’ve left my date’s apartment for the evening. If I’m seeing more than one woman, would it be tacky to then go have sex with another woman while I’m under the effects of the same Viagra pill? It seems a shame to let multiple erections go to waste.

If you have the social adroitness, speed, and stamina to handle such a maneuver, and if you and the lady are in agreement that the evening’s activities are over, Miss Everhard sees no reason to dissuade you from gathering nectar at the next flower. However, be aware that meeting two sexual assignations in the same evening without leaving either party feeling slighted requires some planning and discretion on your part. This is really no different than if you had a naturally high libido and needed sex several times a day with multiple partners to satisfy yourself; introducing Viagra and its window of opportunity into the equation gives you no excuse to behave like a cad. Even if both women are aware of the arrangement, basic consideration and courtesy should be observed. Let the first woman know ahead of time that you are only available for a quickie, and tell her when you need to take your leave so she doesn’t feel like you’re running out on her. You should also allow some time in between dates to shower and change clothes, since your second lady friend would probably not appreciate the scent of another woman on you. And neither woman needs to be reminded that they are not the only beneficiary of your Viagra-enhanced attentions that evening.

Viagra ‘aids muscular dystrophy’

June 7th, 2008 by admin

The anti-impotence drug Viagra may help save people with muscular dystrophy from an early death, a study suggests.

Researchers found the way the drug works to combat impotence may also help ward off heart failure in muscular dystrophy patients.

Tests on mice with a version of the disease showed the drug helped keep their hearts working well.

The Montreal Heart Institute study appears in Proceedings of the National Academy of Sciences.

Muscular dystrophy is a genetic condition causing wasting of the muscles.

The first signs of muscular weakness appear at roughly age five, leading to a progressive loss in the ability to walk by the age of 13.

People with the condition are also at a higher risk of heart failure due to a weakening of the muscles which keep the organ pumping strongly.

For this reason, many people with Duchenne muscular dystrophy - the most common form of the condition - die in early life, often in their 20s or 30s.

Blood flow

The Montreal team found that Viagra - known technically as sildenafil - prevents the loss of a molecule, cGMP, which plays a key role in keeping blood vessels dilated.

In the penis, this increases blood flow, and helps to combat impotence.

But in the heart it helps to ensure the organ itself receives a proper supply of blood, and remains healthy and strong.

With the heart in a strong condition, it is more able to withstand the impact of weakening muscle cells caused by muscular dystrophy.

Viagra works by blocking an enzyme, PDE5, which breaks down cGMP.

Professor Jean-Claude Tardif, director of the Montreal Heart Institute Research Centre, said: “These experimental results give us hope that one day it will be possible to treat with this approach cardiac problems in patients with muscular dystrophy, and perhaps even treat other heart diseases.”

The researchers also inserted a gene that increased cGMP production in the mice’s heart cells, and found that this helped the animals to maintain normal cardiac function.

Dr Marita Pohlschmidt, director of research at the Muscular Dystrophy Campaign, said the research was interesting.

However, she added: “It is important to remember that benefits seen in animals do not always translate into human medicine.

“Although this is promising, it is still very early days and we look forward to further research that will demonstrate the impact it might have for people with muscular dystrophy.”

Solving Sexual Problems with Viagra

May 30th, 2008 by admin

How it works

Taking Viagra relaxes the blood vessels in the penis. This allows blood to flow into the penis causing an erection. However, it will only help you get an erection if you’re sexually stimulated. Viagra isn’t an aphrodisiac and it doesn’t increase your sex drive.
How to take it

Viagra is available in three doses: 25mg, 50mg and 100mg. Your doctor will select the dose most suitable for you. The tablet should be swallowed whole with some water about an hour before sexual activity.

Viagra works better on an empty stomach, so it’s best to avoid having a large meal or a lot of alcohol before taking the tablet.

It takes about 20 minutes to an hour to work and is effective for about four hours. Within this four-hour period you should be able to get an erection in response to sexual stimulation.
Possible side effects

Side effects are generally mild and brief, with the most common side effects being headaches and facial flushing. Less often, men have reported indigestion, a runny nose and a blue tint to the vision.
Does it work for everyone?

Although a safe and effective drug, Viagra isn’t suitable for everyone and doesn’t work in all cases. If you fall into either category, your doctor can advise you of other effective treatment options.

Viagra reduces blood pressure slightly, which isn’t a problem in most men. However, this effect is greatly exaggerated if taken with nitrate treatment, which is prescribed for angina (chest pain). Viagra taken with this will cause a large drop in blood pressure which could prove fatal. If you’re taking nitrates, you shouldn’t take Viagra.

Viagra isn’t licensed for use in women and its safety in women hasn’t been established.

If you have a heart condition it’s important that you discuss your condition and medication with your doctor before taking Viagra. Men who have any of the following conditions should also avoid taking it:

  • severe heart or liver problems
  • recent stroke or heart attack
  • low blood pressure
  • certain rare inherited eye diseases